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CD357 (AITR/GITR) Mouse anti-Human, Alexa Fluor 488, Clone: eBioAITR, eBioscience™

Mouse Monoclonal Antibody

$303.05 - $390.05

Specifications

Antigen CD357 (AITR/GITR)
Clone eBioAITR
Host Species Mouse
Gene Alias TNFRSF18, activation-inducible TNFR family member
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016775

 
affymetrix
53587541
25 tests Each for $303.05

5016776

 
affymetrix
53587542
100 tests Each for $390.05
Description & Specifications

Specifications

Antigen CD357 (AITR/GITR)
Clone eBioAITR
Host Species Mouse
Gene Alias TNFRSF18, activation-inducible TNFR family member
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The monoclonal antibody reacts with human AITR, Activation Inducible TNFR family member, an approximately 25kDa member of the TNFR superfamily. AITR mRNA is detected in lymph node, peripheral blood leukocytes and weakly in spleen. AITR mRNA expression was upregulated within 24 hour on PMA/ionomycin or PHA stimulated PBMC. At the protein level, AITR is expressed by a small population of activated PBMC. AITR associates with TRAF1, TRAF2 and TRAF3 and induces nuclear factor NF-κB activation via TRAF2. Recently TL6 (AITRL) has been reported as the ligand for AITR. Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells.