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CD339 (Jagged 1) Armenian Hamster anti-Mouse, Rat, PE, Clone: HMJ1-29, eBioscience™

Armenian Hamster Monoclonal Antibody

$216.05 - $433.55

Specifications

Antigen CD339 (Jagged 1)
Clone HMJ1-29
Host Species Armenian Hamster
Gene Alias JAG1, Jagged1
Species Reactivity Mouse, Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010762

 
affymetrix
12-3391-80
25μg Each for $216.05

5010763

 
affymetrix
12339182
100μg Each for $433.55
Description & Specifications

Specifications

Antigen CD339 (Jagged 1)
Clone HMJ1-29
Host Species Armenian Hamster
Gene Alias JAG1, Jagged1
Species Reactivity Mouse, Rat
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen.

The HMJ1-29 antibody is reported to crossreact to rat.