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CD336 (NKp44) Mouse anti-Human, Clone: 44.189, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$249.48 - $526.68

Specifications

Antigen CD336 (NKp44)
Clone 44.189
Host Species Murine
Gene Alias NCR2
Applications Flow Cytometry,Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122956 Life Technologies
LS16336982
100μg Each for $249.48
501122957 Life Technologies
LS16336985
500μg Each for $526.68
Specifications

Description

The monoclonal antibody 44.189 reacts with human CD336, which is also known as NKp44 or NCR2. CD336 is a 44kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.

The 44.189 antibody has been reported to facilitate CD336 crosslinking.
Description & Specifications

Specifications

CD336 (NKp44)
Murine
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
44.189
NCR2
RUO
Purified
Primary
aqueous buffer, no sodium azide