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CD335 (NKp46) Rat anti-Mouse, PerCP-eFluor 710, Clone: 29A1.4, eBioscience™

Rat Monoclonal Antibody

$147.84 - $434.28

Specifications

Antigen CD335 (NKp46)
Clone 29A1.4
Host Species Rat
Gene Alias NCR1, Ly-94
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5016037 Life Technologies
LS46335180
25μg Each for $147.84
501130801 Life Technologies
LS46335182
100μg Each for $434.28
Specifications

Description

The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines.

The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo.
Description & Specifications

Specifications

CD335 (NKp46)
Rat
Flow Cytometry
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
29A1.4
NCR1, Ly-94
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer