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CD335 (NKp46) Rat anti-Mouse, Clone: 29A1.4, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$196.68 - $487.08

Specifications

Antigen CD335 (NKp46)
Clone 29A1.4
Host Species Rat
Gene Alias NCR1, Ly-94
Applications Flow Cytometry,Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014520 Life Technologies
LS16335181
50μg Each for $196.68
5014521 Life Technologies
LS16335185
500μg Each for $487.08
Specifications

Description

The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines.

The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo.
Description & Specifications

Specifications

CD335 (NKp46)
Rat
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
29A1.4
NCR1, Ly-94
RUO
Purified
Primary
aqueous buffer, no sodium azide