Please login to your online account to display your discounted pricing

CD335 (NKp46) Rat anti-Mouse, Biotin, Clone: 29A1.4, eBioscience™

Rat Monoclonal Antibody

$85.55 - $201.55

Specifications

Antigen CD335 (NKp46)
Clone 29A1.4
Host Species Rat
Gene Alias NCR1, Ly-94
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122537

 
affymetrix
13335180
25μg Each for $85.55

501122538

 
affymetrix
13335182
100μg Each for $201.55
Description & Specifications

Specifications

Antigen CD335 (NKp46)
Clone 29A1.4
Host Species Rat
Gene Alias NCR1, Ly-94
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines.

The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo.