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CD32b Mouse anti-Mouse, APC, Clone: AT130-2, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $433.55

Specifications

Antigen CD32b
Clone AT130-2
Host Species Mouse
Gene Alias FcRII-b
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123042

 
affymetrix
17032180
25μg Each for $187.05

501123043

 
affymetrix
17032182
100μg Each for $433.55
Description & Specifications

Specifications

Antigen CD32b
Clone AT130-2
Host Species Mouse
Gene Alias FcRII-b
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The monoclonal antibody AT130-2 reacts with mouse CD32b, also known as Fc-gamma receptor IIb. CD32b is the only inhibitory member of the Fc-gamma receptor family. Immune complex engagement of CD32b results in the phosphorylation of its intracellular ITIM motif. This engagement serves to attenuate B cell receptor (BCR) signaling and other activating signals, reduces proliferation, reduces antibody production, and may also deliver apoptotic signals. CD32b is the only Fc-gamma receptor expressed by B cells. CD32b is also expressed on monocytes, dendritic cells, neutrophils, eosinophils and basophils, as well as B cell progenitors and plasma cells.

AT130-2 has been reported to have agonist activity.