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CD326 (EpCAM) Rat anti-Mouse, APC-eFluor 780, Clone: G8.8, eBioscience™

Rat Monoclonal Antibody

$181.25 - $448.05

Specifications

Antigen CD326 (EpCAM)
Clone G8.8
Host Species Rat
Gene Alias epithelial cell adhesion molecule
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124058

 
affymetrix
47579180
25μg Each for $181.25

501124059

 
affymetrix
47579182
100μg Each for $448.05
Description & Specifications

Specifications

Antigen CD326 (EpCAM)
Clone G8.8
Host Species Rat
Gene Alias epithelial cell adhesion molecule
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC-eFluor 780
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The G8.8 monoclonal antibody reacts with the 40kDa protein mouse EpCAM (epithelial cellular adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326. The immunogen used to generate the G8.8 antibody was the TE-71 thymic epithelial cell line. CD326 is expressed on the majority of epithelial cells, and is considered a pan-carcinoma antigen. CD326 mediates calcium-independent, homophilic, cell-cell adhesion and may function as a growth factor receptor. The antigen is being used as a target for immunotherapy treatment of human carcinomas. CD326 binds LAIR-1 (CD305) and LAIR-2 (CD306) to inhibit cellular activation and inflammation. This epithelial glycoprotein is now recognized as having an important role in tumor biology.