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CD325 (N-cadherin) Mouse anti-Human, Biotin, Clone: 8C11, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $651.05

Specifications

Antigen CD325 (N-cadherin)
Clone 8C11
Host Species Mouse
Gene Alias neural cadherin
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011835

 
affymetrix
13325980
25μg Each for $158.05

5011836

 
affymetrix
13325982
100μg Each for $332.05

5011837

 
affymetrix
13325985
500μg Each for $651.05
Description & Specifications

Specifications

Antigen CD325 (N-cadherin)
Clone 8C11
Host Species Mouse
Gene Alias neural cadherin
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 8C11 monoclonal antibody reacts with human CD325, also known as N-Cadherin. CD325 is a 130kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells.