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CD32 Mouse anti-Human, Clone: 6C4 (CD32), Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$158.05 - $506.05

Specifications

Antigen CD32
Clone 6C4 (CD32)
Host Species Mouse
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014289

 
affymetrix
16032981
50μg Each for $158.05

501128812

 
affymetrix
16-0329-85
500μg Each for $506.05
Description & Specifications

Specifications

Antigen CD32
Clone 6C4 (CD32)
Host Species Mouse
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Species Reactivity Human
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.