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CD32 Mouse anti-Human, APC, Clone: 6C4 (CD32), eBioscience™

Mouse Monoclonal Antibody

$201.55 - $404.55

Specifications

Antigen CD32
Clone 6C4 (CD32)
Host Species Mouse
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014944

 
affymetrix
17-0329-41
25 tests Each for $201.55

5014945

 
affymetrix
17032942
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen CD32
Clone 6C4 (CD32)
Host Species Mouse
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.5μg)/test

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.