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CD317 (BST2/PDCA-1) Mouse anti-Human, Clone: 26F8, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$172.55 - $375.55

Specifications

Antigen CD317 (BST2/PDCA-1)
Clone 26F8
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014518

 
life technologies
LS16317980
25μg Each for $172.55

5014519

 
life technologies
LS16317982
100μg Each for $375.55
Description & Specifications

Specifications

Antigen CD317 (BST2/PDCA-1)
Clone 26F8
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

This 26F8 monoclonal antibody reacts with human CD317 (also known as BST2 and tetherin). CD317 is a 30-36kDa type II transmembrane protein expressed on B cells and bone marrow stromal cells. Although reports have indicated that CD317 mRNA is detectable in activated T cells, protein expression in primary T cells and macrophages is undetectable. Moreover, certain T cell lines, such as Jurkat, do not express detectable levels of CD317 protein. CD317 has been associated with pre-B cell growth and the terminal differentiation of plasma B cells. More recently, this molecule has been reported to prevent HIV-1 virion release from the surface of infected cells, leading to reuptake and degradation of the virus. This activity is inhibited by the HIV-1 accessory protein Vpu. CD317 has been identified as the ligand for the ILT7 receptor.