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CD314 (NKG2D) Mouse anti-Human, PE-Cy7, Clone: 1D11, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $376.20

Specifications

Antigen CD314 (NKG2D)
Clone 1D11
Host Species Murine
Gene Alias KLRK1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123402 Life Technologies
LS25587841
25 Tests Each for $170.28
501123403 Life Technologies
LS25587842
100 Tests Each for $376.20
Specifications

Description

The 1D11 monoclonal antibody reacts with the human NKG2D, a 42kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
Description & Specifications

Specifications

CD314 (NKG2D)
Murine
Flow Cytometry
PE-Cy7
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
5μL (0.25μg)/test
1D11
KLRK1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer