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CD314 (NKG2D) Mouse anti-Human, PE, Clone: 5C6, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $361.05

Specifications

Antigen CD314 (NKG2D)
Clone 5C6
Host Species Murine
Gene Alias KLRK1
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010932 Life Technologies
LS12587941
25 Tests Each for $158.05
5010933 Life Technologies
LS12587942
100 Tests Each for $361.05
Specifications

Description

The 5C6 monoclonal antibody reacts with the human NKG2D, a 42kDa lectin-like molecule expressed by NK cells, γδ T cells, some CD4+ and CD8+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to γδ TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
Description & Specifications

Specifications

CD314 (NKG2D)
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
5C6
KLRK1
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test