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CD314 (NKG2D) Mouse anti-Human, PE, Clone: 1D11, eBioscience™

Mouse Monoclonal Antibody

$143.88 - $328.68

Specifications

Antigen CD314 (NKG2D)
Clone 1D11
Host Species Murine
Gene Alias KLRK1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010930 Life Technologies
LS12587841
25 Tests Each for $143.88
5010931 Life Technologies
LS12587842
100 Tests Each for $328.68
Specifications

Description

The 1D11 monoclonal antibody reacts with the human NKG2D, a 42kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
Description & Specifications

Specifications

CD314 (NKG2D)
Murine
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test
1D11
KLRK1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer