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CD314 (NKG2D) Mouse anti-Human, Clone: 1D11, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $288.55

Specifications

Antigen CD314 (NKG2D)
Clone 1D11
Host Species Murine
Gene Alias KLRK1
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013255 Life Technologies
LS14587882
100μg Each for $288.55
5013254 Life Technologies
LS14587880
25μg Each for $143.55
Specifications

Description

The 1D11 monoclonal antibody reacts with the human NKG2D, a 42kDa lectin-like molecule expressed by NK cells, gamma delta T cells, CD8+ T cells, and some CD4+ T cells. Human NKG2D forms complexes with DAP10, a membrane adaptor protein, and has the ability to costimulate multiple NK activation receptors. The counter-receptor for human NKG2D has been identified as MICA/MICB expressed on epithelial tumors from lung, breast, kidney, ovary, prostate and colon carcinoma. 5C6 and 1D11 block binding of soluble MICA to gamma delta TCR T cell clones and inhibit lysis by these cells. 5C6 and 1D11 induced NKG2D function of redirected lysis of FcReceptor bearing P815 cells.
Description & Specifications

Specifications

CD314 (NKG2D)
Murine
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
1D11
KLRK1
Flow Cytometry,Functional Assay,Immunohistochemistry (Frozen),Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL