Please login to your online account to display your discounted pricing

CD307e (FcRL5) Mouse anti-Human, eFluor 660, Clone: 509F6, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $462.55

Specifications

Antigen CD307e (FcRL5)
Clone 509F6
Host Species Mouse
Gene Alias Fc receptor-like 5, IRTA2
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124334

 
affymetrix
50307841
25 tests Each for $187.05

501124335

 
affymetrix
50307842
100 tests Each for $462.55
Description & Specifications

Specifications

Antigen CD307e (FcRL5)
Clone 509F6
Host Species Mouse
Gene Alias Fc receptor-like 5, IRTA2
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 660
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (1.0μg)/test

The 509F6 monoclonal antibody reacts with human CD307e which is also known as Fc receptor-like 5, FcRL5, FcRH5, or IRTA2. CD307e is a surface protein expressed selectively on naïve mature B cells and on bone marrow plasma cells, and binds to all IgG isotypes. CD307e functions as an inhibitory coreceptor on mature B cells in humans via the recruitment of the phosphatase SHP-1 to its two immunoreceptor tyrosine-based inhibitory motifs (ITIM). CD307e can also exist in soluble form and high levels of soluble CD307e have been detected in the blood of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma. Because surface-bound CD307e is also highly-expressed on malignant B cells from multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma patients, CD307e may be a useful therapeutic target for the treatment of these cancers.