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CD307e (FcRL5) Mouse anti-Human, eFluor 660, Clone: 509F6, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $462.55

Specifications

Antigen CD307e (FcRL5)
Clone 509F6
Host Species Murine
Gene Alias Fc receptor-like 5, IRTA2
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124334 Life Technologies
LS50307841
25 Tests Each for $187.05
501124335 Life Technologies
LS50307842
100 Tests Each for $462.55
Specifications

Description

The 509F6 monoclonal antibody reacts with human CD307e which is also known as Fc receptor-like 5, FcRL5, FcRH5, or IRTA2. CD307e is a surface protein expressed selectively on naïve mature B cells and on bone marrow plasma cells, and binds to all IgG isotypes. CD307e functions as an inhibitory coreceptor on mature B cells in humans via the recruitment of the phosphatase SHP-1 to its two immunoreceptor tyrosine-based inhibitory motifs (ITIM). CD307e can also exist in soluble form and high levels of soluble CD307e have been detected in the blood of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma. Because surface-bound CD307e is also highly-expressed on malignant B cells from multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma patients, CD307e may be a useful therapeutic target for the treatment of these cancers.
Description & Specifications

Specifications

CD307e (FcRL5)
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
509F6
Fc receptor-like 5, IRTA2
Flow Cytometry
eFluor 660
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (1.0μg)/test