missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD300e (IREM-2) Mouse anti-Human, PE, Clone: UP-H2, eBioscience™

Mouse Monoclonal Antibody

$209.88 - $394.68

Specifications

Antigen CD300e (IREM-2)
Clone UP-H2
Host Species Murine
Gene Alias IREM2, CLM-2
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010744 Life Technologies
LS12300741
25 Tests Each for $209.88
5010745 Life Technologies
LS12300742
100 Tests Each for $394.68
Specifications

Description

The monoclonal antibody UP-H2 recognizes human IREM-2 (immune receptor expressed in monocytic derived cells) also known as LMIR6, and unofficially CD300E and CD300LE. It is a member of the CMRF-35 family. This 34kDa Ig-like containing receptor is an activating receptor and through it’s charged residues in the cytokplasmic domain interacts with ITAM containing adaptor proteins like DAP12. Expression is found exclusively on monocytes and myeloid DC’s. Expression may be transient as differentiation of monocytes leads to down regulation of IREM-2 yet expression is found on mature DCs. It has been also noted that myeloid cell lines such as THP-1 and U937 do not express IREM-2.
In vitro addition of UP-H2 antibody either soluble or crosslinked stimulates monocytes.
Description & Specifications

Specifications

CD300e (IREM-2)
Murine
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test
UP-H2
IREM2, CLM-2
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer