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CD3 Mouse anti-Rat, APC, Clone: G4.18, eBioscience™

Mouse Monoclonal Antibody

$100.05 - $259.55

Specifications

Antigen CD3
Clone eBioG4.18 (G4.18)
Host Species Mouse
Gene Alias T3
Species Reactivity Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123025

 
affymetrix
17003080
25μg Each for $100.05

501123026

 
affymetrix
17003082
100μg Each for $259.55
Description & Specifications

Specifications

Antigen CD3
Clone eBioG4.18 (G4.18)
Host Species Mouse
Gene Alias T3
Species Reactivity Rat
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. \i{in vitro\i}, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. \i{in vivo\i}, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft.