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CD3 Mouse anti-Human, FITC, Clone: OKT3, eBioscience™

Mouse Monoclonal Antibody

$114.55 - $274.05

Specifications

Antigen CD3
Clone OKT3
Host Species Mouse
Gene Alias Leu-4, T3
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

509366

 
affymetrix
11-0037-41
25 tests Each for $114.55

501129433

 
affymetrix
11-0037-42
100 tests Each for $274.05
Description & Specifications

Specifications

Antigen CD3
Clone OKT3
Host Species Mouse
Gene Alias Leu-4, T3
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (1μg)/test

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.