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CD284 (TLR4) Mouse anti-Mouse, Alexa Fluor 488, Clone: UT41, eBioscience™

Mouse Monoclonal Antibody

$223.08 - $394.68


Antigen CD284 (TLR4)
Clone UT41
Host Species Murine
Gene Alias TLR-4, toll-like receptor 4
Applications Flow Cytometry
View More Specs


For Research Use Only.

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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5016828 Life Technologies
25μg Each for $223.08
5016829 Life Technologies
100μg Each for $394.68


The UT41 monoclonal antibody was generated against BaF3 cells overexpressing mouse TLR4. So far, at least twelve members of the Toll family have been identified. This family of type I transmembrane protein is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR4 physically associates with another molecule called MD-2, and together with CD14, this complex is responsible for LPS recognition and signaling. TLR4, which is approximately 100 kDa, is expressed by myeloid lineage cells.

The MTS510 monoclonal antibody co-immunoprecipitates MD-2 (∽30 kDa) and TLR4 (∽100 kDa), and preferentially reacts with TLR4 that is associated with MD-2. In comparison, binding of the UT41 monoclonal antibody occurs with and without formation of the TLR4/MD-2 complex . Please contact eBioscience Technical Support for further information.
Description & Specifications


CD284 (TLR4)
Flow Cytometry
Alexa Fluor 488
Store at 2-8°C. Do not freeze. Light-sensitive material.
TLR-4, toll-like receptor 4
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer