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CD283 (TLR3) Mouse anti-Human, Clone: TLR3.7, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $368.28

Specifications

Antigen CD283 (TLR3)
Clone TLR3.7
Host Species Murine
Gene Alias TLR-3, toll-like receptor 3
Applications Flow Cytometry (Intracellular Staining),Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013786 Life Technologies
LS14903980
25μg Each for $170.28
5013787 Life Technologies
LS14903982
100μg Each for $368.28
Specifications

Description

The TLR3.7 monoclonal antibody reacts with human Toll-like receptor 3 (TLR3). To date, at least twelve members of the Toll-like receptor family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immune response, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial activity. TLR3 recognizes double-stranded (ds)RNA, induces the activation of NF-κB through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). TLR3.7 suppressed poly(I):poly(C)-mediated IFN-β production by human fibroblasts naturally expressing TLR3 on their surface.
Description & Specifications

Specifications

CD283 (TLR3)
Murine
Flow Cytometry (Intracellular Staining),Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
TLR3.7
TLR-3, toll-like receptor 3
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer