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CD282 (TLR2) Rat anti-Mouse, Clone: 6C2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$216.05 - $549.55

Specifications

Antigen CD282 (TLR2)
Clone 6C2
Host Species Rat
Gene Alias TLR-2, toll-like receptor 2
Species Reactivity Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014772

 
affymetrix
16-9021-81
50μg Each for $216.05

5014773

 
affymetrix
16-9021-83
200μg Each for $549.55
Description & Specifications

Specifications

Antigen CD282 (TLR2)
Clone 6C2
Host Species Rat
Gene Alias TLR-2, toll-like receptor 2
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The 6C2 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.