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CD282 (TLR2) Mouse anti-Human, Clone: TL2.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$390.05 - $2,898.55

Specifications

Antigen CD282 (TLR2)
Clone TL2.1
Host Species Mouse
Gene Alias toll-like receptor 2
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123014

 
affymetrix
16992238
5mg Each for $2,898.55

501123015

 
affymetrix
16992282
100μg Each for $390.05
Description & Specifications

Specifications

Antigen CD282 (TLR2)
Clone TL2.1
Host Species Mouse
Gene Alias toll-like receptor 2
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The TL2.1 monoclonal antibody reacts with human Toll-like receptor 2 (TLR2). To date, at least ten members of the Toll family have been identified in human. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed by peripheral blood monocytes and is responsible for distinguishing different pathogens. TL2.1, a blocking antibody, has been used to study the role of TLR-2 as a pattern recognition receptor in microbial lipoprotein/lipopeptide induced cytokine production from human peripheral blood mononuclear cells. TL2.1 has been reported to immunoprecipitate human TLR2 (~90kDa) from PBMC and HMEC.