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CD282 (TLR2) Mouse anti-Human, Clone: TL2.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$355.08 - $2,638.68

Specifications

Antigen CD282 (TLR2)
Clone TL2.1
Host Species Murine
Gene Alias toll-like receptor 2
Applications Flow Cytometry,Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123014 Life Technologies
LS16992238
5mg Each for $2,638.68
501123015 Life Technologies
LS16992282
100μg Each for $355.08
Specifications

Description

The TL2.1 monoclonal antibody reacts with human Toll-like receptor 2 (TLR2). To date, at least ten members of the Toll family have been identified in human. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed by peripheral blood monocytes and is responsible for distinguishing different pathogens. TL2.1, a blocking antibody, has been used to study the role of TLR-2 as a pattern recognition receptor in microbial lipoprotein/lipopeptide induced cytokine production from human peripheral blood mononuclear cells. TL2.1 has been reported to immunoprecipitate human TLR2 (~90kDa) from PBMC and HMEC.
Description & Specifications

Specifications

CD282 (TLR2)
Murine
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
TL2.1
toll-like receptor 2
RUO
Purified
Primary
aqueous buffer, no sodium azide, functional Grade