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CD279 (PD-1) Rat anti-Mouse, Clone: RMP1-14, eBioscience™

Rat Monoclonal Antibody

$143.88 - $368.28

Specifications

Antigen CD279 (PD-1)
Clone RMP1-14
Host Species Rat
Applications Flow Cytometry,Functional Assay
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122897 Life Technologies
LS14998285
500μg Each for $368.28
5013958 Life Technologies
LS14998281
50μg Each for $143.88
5013959 Life Technologies
LS14998282
100μg Each for $196.68
Specifications

Description

This antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Similar to J43, another mAb to mouse PD-1 (cat. 16-9985), RMP1-14 blocks the binding of both B7-H1-Ig and B7-DC-Ig to PD-1 transfectants.
Description & Specifications

Specifications

CD279 (PD-1)
Rat
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
RMP1-14
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL