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CD279 (PD-1) Rat anti-Mouse, Clone: RMP1-14, eBioscience™

Rat Monoclonal Antibody

$158.05 - $404.55

Specifications

Antigen CD279 (PD-1)
Clone RMP1-14
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122897

 
affymetrix
14998285
500μg Each for $404.55

5013958

 
affymetrix
14998281
50μg Each for $158.05

5013959

 
affymetrix
14998282
100μg Each for $216.05
Description & Specifications

Specifications

Antigen CD279 (PD-1)
Clone RMP1-14
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Similar to J43, another mAb to mouse PD-1 (cat. 16-9985), RMP1-14 blocks the binding of both B7-H1-Ig and B7-DC-Ig to PD-1 transfectants.