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CD279 (PD-1) Rat anti-Mouse, APC, Clone: RMP1-30, eBioscience™

Rat Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen CD279 (PD-1)
Clone RMP1-30
Host Species Rat
Gene Alias Pdcd1, Programmed cell death protein 1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245711

 
affymetrix
17998180
25μg Each for $143.55

50245712

 
affymetrix
17998182
100μg Each for $361.05
Description & Specifications

Specifications

Antigen CD279 (PD-1)
Clone RMP1-30
Host Species Rat
Gene Alias Pdcd1, Programmed cell death protein 1
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.