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CD279 (PD-1) Mouse anti-Human, PE, Clone: eBioJ105 (J105), eBioscience™

Mouse Monoclonal Antibody

$201.55 - $404.55

Specifications

Antigen CD279 (PD-1)
Clone eBioJ105 (J105)
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010743

 
affymetrix
12279941
25 tests Each for $201.55

501129426

 
affymetrix
12-2799-42
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen CD279 (PD-1)
Clone eBioJ105 (J105)
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.5μg)/test

The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.

Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969).