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CD279 (PD-1) Mouse anti-Human, APC-eFluor 780, Clone: eBioJ105 (J105), eBioscience™

Mouse Monoclonal Antibody

$187.44 - $469.92

Specifications

Antigen CD279 (PD-1)
Clone eBioJ105 (J105)
Host Species Murine
Applications Flow Cytometry
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124049 Life Technologies
LS47279941
25 Tests Each for $187.44
501128858 Life Technologies
LS47279942
100 Tests Each for $469.92
Specifications

Description

The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.

Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969).
Description & Specifications

Specifications

CD279 (PD-1)
Murine
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBioJ105 (J105)
Flow Cytometry
APC-eFluor 780
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
5μL (0.125μg)/test