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CD278 (ICOS) Rat anti-Mouse, Clone: 7E.17G9, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$158.05 - $433.55

Specifications

Antigen CD278 (ICOS)
Clone 7E.17G9
Host Species Rat
Gene Alias Inducible T-cell co-stimulator
Species Reactivity Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014806

 
affymetrix
16994281
50μg Each for $158.05

5014807

 
affymetrix
16-9942-85
500μg Each for $433.55
Description & Specifications

Specifications

Antigen CD278 (ICOS)
Clone 7E.17G9
Host Species Rat
Gene Alias Inducible T-cell co-stimulator
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.