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CD273 (B7-DC) Rat anti-Mouse, PerCP-eFluor 710, Clone: 122, eBioscience™

Rat Monoclonal Antibody

$157.08 - $394.68

Specifications

Antigen CD273 (B7-DC)
Clone 122
Host Species Rat
Gene Alias PD-L2
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123987 Life Technologies
LS46997282
100μg Each for $394.68
501129762 Life Technologies
LS46997280
25μg Each for $157.08
Specifications

Description

The 122 monoclonal antibody reacts with mouse B7-DC, also known as PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of approximately 25kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages in the mouse. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. 122 has been demonstrated to block binding of TY25 (Cat. No. 14-5986), another mAb specific for mouse B7-DC.
Description & Specifications

Specifications

CD273 (B7-DC)
Rat
Flow Cytometry
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
122
PD-L2
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer