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CD273 (B7-DC) Rat anti-Mouse, Clone: TY25, eBioscience™

Rat Monoclonal Antibody

$130.68 - $434.28

Specifications

Antigen CD273 (B7-DC)
Clone TY25
Host Species Rat
Gene Alias B7DC, PD-L2, PDL-2, PDL2
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013408 Life Technologies
LS14598681
50μg Each for $130.68
5013409 Life Technologies
LS14598682
100μg Each for $249.48
5013410 Life Technologies
LS14598685
500μg Each for $434.28
Specifications

Description

The TY25 monoclonal antibody reacts with mouse B7-DC/PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of ∽25kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by sub-populations of dendritic cells, monocytes and macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, but binds PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. TY25 is a useful tool to study the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in mouse.
Description & Specifications

Specifications

CD273 (B7-DC)
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TY25
B7DC, PD-L2, PDL-2, PDL2
Flow Cytometry,Functional Assay,Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL