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CD273 (B7-DC) Rat anti-Mouse, Clone: 122, eBioscience™

Rat Monoclonal Antibody

$158.05 - $564.05

Specifications

Antigen CD273 (B7-DC)
Clone 122
Host Species Rat
Gene Alias PD-L2
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013946

 
affymetrix
14-9972-85
500μg Each for $564.05

5013944

 
affymetrix
14997281
50μg Each for $158.05
Description & Specifications

Specifications

Antigen CD273 (B7-DC)
Clone 122
Host Species Rat
Gene Alias PD-L2
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 122 monoclonal antibody reacts with mouse B7-DC, also known as PD-L2. B7-DC, a recently identified member of the B7 family, has a predicted molecular weight of approximately 25kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages in the mouse. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. 122 has been demonstrated to block binding of TY25 (Cat. No.14-5986), another mAb specific for mouse B7-DC.