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CD270 (HVEM) Armenian Hamster anti-Mouse, Clone: LH1, eBioscience™

Armenian Hamster Monoclonal Antibody

$129.05 - $361.05

Specifications

Antigen CD270 (HVEM)
Clone LH1
Host Species Armenian Hamster
Gene Alias herpes virus entry mediator, TNFRSF14, LIGHTR
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013370 Life Technologies
LS14596280
25μg Each for $129.05
5013371 Life Technologies
LS14596282
100μg Each for $361.05
Specifications

Description

The LH1 monoclonal antibody reacts with mouse Herpes Virus Entry Mediator (HVEM, TR2), a member of the TNF-receptor superfamily. HVEM is found on most cell types, including T cells, B cells, monocytes, neutrophils and dendritic cells. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of HVEM was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. HVEM has also been demonstrated to be a unique ligand for BTLA (B and T lymphocyte attenuator). The conservation of the BTLA-HVEM interaction between mouse and human suggests that this system is an important pathway regulating lymphocyte activation and/or homeostasis in the immune response. The LH1 antibody has been reported as a blocking antibody, interfering with the HVEM-LIGHT interaction but not the HVEM-BTLA interaction.
Description & Specifications

Specifications

CD270 (HVEM)
Armenian Hamster
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
LH1
herpes virus entry mediator, TNFRSF14, LIGHTR
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL