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Thermo Scientific™ Lab Vision™ CD27 Ab-2, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ CD27 Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1468S1

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Catalog No. MS1468S1

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Description & Specifications

Specifications

Antigen CD27 Ab-2
Format Concentrated
Host Species Mouse
Applications Immunohistochemistry (Paraffin)
Immunogen Recombinant human CD27 protein
Isotype IgG1
Regulatory Status RUO
Clone 137B4
Quantity 500µL
Cross Reactivity Human
Purification Method Tonsil
Research Discipline Apoptosis
Type Primary
Classification Monoclonal
Conjugate Unlabeled

Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ CD27 Ab-2, Mouse Monoclonal Antibody.

CD27 (also known as S152 or T14) is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell costimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFδB and SAPK/JNK and induces apoptosis.

Host Species: Mouse

Clone: 137B4

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Immunogen: Recombinant human CD27 protein

Molecular Weight: 120 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO