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Thermo Scientific™ Lab Vision™ CD27 Ab-2, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ CD27 Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1468R7

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Catalog No. MS1468R7

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Description & Specifications

Specifications

Format Prediluted
Host Species Mouse
Applications Immunohistochemistry (Paraffin)
Isotype IgG1
Quantity 7mL
Regulatory Status RUO
Antigen CD27 Ab-2
Immunogen Recombinant human CD27 protein
Clone 137B4
Cross Reactivity Human
Research Discipline Apoptosis
Type Primary
Classification Monoclonal
Conjugate Unlabeled

Obtain accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ CD27 Ab-2, Mouse Monoclonal Antibody.

CD27 (also known as S152 or T14) is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell costimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFδB and SAPK/JNK and induces apoptosis.

Host Species: Mouse

Clone: 137B4

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Immunogen: Recombinant human CD27 protein

Molecular Weight: 120 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO