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CD268 (BAFF Receptor) Mouse anti-Human, PE, Clone: 8A7, eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  Life Technologies LS12911741

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Catalog No. 5011252



Description

Description

Description: The 8A7 monoclonal antibody reacts with the human BAFF receptor, also known as B lymphocyte stimulator (BLyS protein) receptor, which is expressed on B cells. The ligand for this receptor, BAFF (B cell-activating factor of the TNF family) is a B cell survival factor and regulates CD21/35 and CD23 expression. Interaction of this ligand with its receptor causes elevated CD21/35 and CD23 expression, whereas receptor blockade has been shown to down-modulate expression. Applications Reported: The 8A7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 8A7 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.00375 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.
Specifications

Specifications

CD268 (BAFF Receptor)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q96RJ3
TNFRSF13C, BAFF-R, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF-R, BLyS receptor 3, TNFRSF13C, BAFFR, BR3
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
8A7
PE
TNFRSF13C
Liquid
TNFRSF13C
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
115650
Documents

For Research Use Only.