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CD267 (TACI) Mouse anti-Human, Clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $288.55

Specifications

Antigen CD267 (TACI)
Clone 11H3
Host Species Mouse
Gene Alias TNFRSF13B
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5013810

 
affymetrix
14921782
100μg Each for $288.55

5013809

 
affymetrix
14-9217-80
25μg Each for $143.55
Description & Specifications

Specifications

Antigen CD267 (TACI)
Clone 11H3
Host Species Mouse
Gene Alias TNFRSF13B
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.