missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD265 (RANK) Rat anti-Mouse, PE, Clone: R12-31, eBioscience™

Rat Monoclonal Antibody

$170.28 - $302.28

Specifications

Antigen CD265 (RANK)
Clone R12-31
Host Species Rat
Gene Alias Receptor Activator of NF-kB
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011094 Life Technologies
LS12661281
50μg Each for $170.28
501122369 Life Technologies
LS12661282
100μg Each for $302.28
Specifications

Description

The R12-31 monoclonal antibody reacts with mouse RANK (Receptor activator of NF-κB), a recently cloned member of the TNFR superfamily with no significant homology to other members of this family. RANK ligand (RANKL/TRANCE/ OPGL) binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL suggesting a role in dendritic cell survival. The cytoplasmic domain of RANK interacts with TRAF2, TRAF5 and TRAF6. Overexpression of RANK activates NF-κB and c-Jun-terminal kinase (JNK) pathways. Recent studies have shown that RANK interaction with TRAF6 activates NF-κB, whereas JNK activation is mediated through binding of RANK to TRAF2.
Description & Specifications

Specifications

CD265 (RANK)
Rat
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
R12-31
Receptor Activator of NF-kB
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer