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CD258 (LIGHT) Mouse anti-Human, PE, Clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

$433.55 - $433.55

Specifications

Antigen CD258 (LIGHT)
Clone 7-3 (7)
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010742

 
life technologies
LS12258942
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CD258 (LIGHT)
Clone 7-3 (7)
Host Species Mouse
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This 7-3 (7) monoclonal antibody reacts with human CD258 (also known as LIGHT), a 29kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-ß (LT-ß). Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator (HVEM), LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-ß receptor.