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CD254 (RANK Ligand) Mouse anti-Human, PE, Clone: MIH24, eBioscience™

Mouse Monoclonal Antibody

$196.68 - $394.68

Specifications

Antigen CD254 (RANK Ligand)
Clone MIH24
Host Species Murine
Gene Alias TRANCE, OPGL, RANKL
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011097 Life Technologies
LS12661980
25μg Each for $196.68
5011098 Life Technologies
LS12661982
100μg Each for $394.68
Specifications

Description

The MIH24 monoclonal antibody reacts with human TRANCE (TNF-related activation-induced cytokine receptor) also known as RANKL (receptor activator of NF-κB ligand) and OPGL (Osteoprotegerin Ligand). TRANCE is a type II membrane protein with predicted molecular weight of 35 kDa. Its extracellular domain is most closely related to TRAIL, FasL and TNF. TRANCE mRNA is upregulated by TCR stimulation. TRANCE-deficient mouse lacks osteoclasts. In addition, TRANCE has been shown to be involved in the interactions between T-dendritic and T-B cells. It was also found to be critical in osteoclast differentiation. The TRANCE-RANK interaction regulates the expression of the anti-apoptotic molecule Bcl-xL.
Description & Specifications

Specifications

CD254 (RANK Ligand)
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
MIH24
TRANCE, OPGL, RANKL
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL