Please login to your online account to display your discounted pricing

CD254 (RANK Ligand) Mouse anti-Human, PE, Clone: MIH24, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $433.55

Specifications

Antigen CD254 (RANK Ligand)
Clone MIH24
Host Species Mouse
Gene Alias TRANCE, OPGL, RANKL
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011097

 
affymetrix
12661980
25μg Each for $216.05

5011098

 
affymetrix
12661982
100μg Each for $433.55
Description & Specifications

Specifications

Antigen CD254 (RANK Ligand)
Clone MIH24
Host Species Mouse
Gene Alias TRANCE, OPGL, RANKL
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The MIH24 monoclonal antibody reacts with human TRANCE (TNF-related activation-induced cytokine receptor) also known as RANKL (receptor activator of NF-κB ligand) and OPGL (Osteoprotegerin Ligand). TRANCE is a type II membrane protein with predicted molecular weight of 35 kDa. Its extracellular domain is most closely related to TRAIL, FasL and TNF. TRANCE mRNA is upregulated by TCR stimulation. TRANCE-deficient mouse lacks osteoclasts. In addition, TRANCE has been shown to be involved in the interactions between T-dendritic and T-B cells. It was also found to be critical in osteoclast differentiation. The TRANCE-RANK interaction regulates the expression of the anti-apoptotic molecule Bcl-xL.