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CD25 Rat anti-Mouse, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

$71.05 - $462.55

Specifications

Antigen CD25
Clone PC61.5
Host Species Rat
Gene Alias Interleukin-2 Receptor alpha
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122636

 
affymetrix
14025181
50μg Each for $71.05

501122637

 
affymetrix
14025186
1mg Each for $462.55

5012487

 
affymetrix
14025185
500μg Each for $288.55
Description & Specifications

Specifications

Antigen CD25
Clone PC61.5
Host Species Rat
Gene Alias Interleukin-2 Receptor alpha
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.