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CD25 Rat anti-Mouse, APC-eFluor 780, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

$158.05 - $419.05

Specifications

Antigen CD25
Clone PC61.5
Host Species Rat
Gene Alias Interleukin-2 Receptor alpha
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016155

 
affymetrix
47025180
25μg Each for $158.05

5016156

 
affymetrix
47025182
100μg Each for $419.05
Description & Specifications

Specifications

Antigen CD25
Clone PC61.5
Host Species Rat
Gene Alias Interleukin-2 Receptor alpha
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC-eFluor 780
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.