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CD25 Rat anti-Mouse, Alexa Fluor 488, Clone: 3C7, eBioscience™

Rat Monoclonal Antibody

$129.05 - $288.55

Specifications

Antigen CD25
Clone eBio3C7 (3C7)
Host Species Rat
Gene Alias Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016696

 
affymetrix
53-0253-80
25μg Each for $129.05

5016697

 
affymetrix
53025382
100μg Each for $288.55
Description & Specifications

Specifications

Antigen CD25
Clone eBio3C7 (3C7)
Host Species Rat
Gene Alias Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBio3C7 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of the IL-2 receptor is inhibited by the 3C7 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) and subsequent detection with another CD25 antibody.