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This monoclonal antibody is cross-reactive to rhesus monkey.Description & Specifications
DescriptionThis CD25-4E3 monoclonal antibody reacts to human CD25, which is also known as the low-affinity interleukin (IL)-2 receptor alpha. CD25 is expressed on activated T cells (including a subset of regulatory T cells), B cells, and macrophages. This receptor subunit associates with CD122, the IL-2 receptor beta chain, and CD132, the common gamma chain, to form the high-affinity IL-2 receptor. IL-2 receptor signaling has been linked to cell proliferation and survival in lymphocytes. CD25 is a marker for Hodgkin’s disease, and has been associated with such autoimmune diseases as Type I diabetes.
This monoclonal antibody is cross-reactive to rhesus monkey.
|Human, Non-human primate|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Interleukin-2 Receptor alpha, IL-2Ra|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|