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CD25 Mouse anti-Canine, PE, Clone: P4A10, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen CD25
Clone P4A10
Host Species Mouse
Gene Alias Interleukin-2 Receptor alpha
Species Reactivity Canine
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010286

 
affymetrix
12025042
100 tests Each for $361.05

5010285

 
affymetrix
12-0250-41
25 tests Each for $143.55
Description & Specifications

Specifications

Antigen CD25
Clone P4A10
Host Species Mouse
Gene Alias Interleukin-2 Receptor alpha
Species Reactivity Canine
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This P4A10 monoclonal antibody reacts with canine CD25, the 55kDa interleukin-2 receptor alpha (IL-2Rα) chain. As in humans and mice, CD25 in dogs is expressed by early T and B lineage progenitors as well as by activated mature T and B lymphocytes. CD25 associates with the IL-2R beta (CD122) and gamma (CD132) chains to form the high-affinity IL-2 receptor. On its own, CD25 binds IL-2 with low affinity. Along with CD4 and Foxp3, CD25 is a major marker used to define regulatory T cells.

The P4A10 antibody has been reported to recognize the same epitope as the anti-human CD25 monoclonal antibody ACT-1, but with greater affinity.