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The P4A10 antibody has been reported to recognize the same epitope as the anti-human CD25 monoclonal antibody ACT-1, but with greater affinity.Description & Specifications
DescriptionThis P4A10 monoclonal antibody reacts with canine CD25, the 55kDa interleukin-2 receptor alpha (IL-2Rα) chain. As in humans and mice, CD25 in dogs is expressed by early T and B lineage progenitors as well as by activated mature T and B lymphocytes. CD25 associates with the IL-2R beta (CD122) and gamma (CD132) chains to form the high-affinity IL-2 receptor. On its own, CD25 binds IL-2 with low affinity. Along with CD4 and Foxp3, CD25 is a major marker used to define regulatory T cells.
The P4A10 antibody has been reported to recognize the same epitope as the anti-human CD25 monoclonal antibody ACT-1, but with greater affinity.
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|