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CD247 (CD3 zeta) Mouse anti-Human, PerCP-eFluor 710, Clone: 6B10.2, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $447.48

Specifications

Antigen CD247 (CD3 zeta)
Clone 6B10.2
Host Species Murine
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123795 Life Technologies
LS46247941
25 Tests Each for $187.05
501123796 Life Technologies
LS46247942
100 Tests Each for $447.48
Specifications

Description

This 6B10.2 monoclonal antibody reacts with human CD247, which is also known as the invariant zeta chain. The CD3 complex is composed of three monomeric chains (γ, δ, and ε) and the invariant zeta chain, which exists as a homodimer or as a heterodimer with the η subunit. Together with the T cell antigen receptor (TCR), the CD3 γ, δ, ε, and zeta chains comprise the TCR/CD3 complex. CD3 zeta is expressed on immature and mature thymocytes, as well as T lymphocytes and NK cells. Signal transduction during T cell activation is mediated by tyrosine phosphorylation of cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs) present on the zeta chain.

The 6B10.2 monoclonal antibody recognizes a transmembrane epitope of the CD3 zeta chain. Therefore, flow cytometric analysis with this antibody requires intracellular staining. In addition, this antibody has been reported to recognize the zeta chain as a homodimer but not as a monomer.
Description & Specifications

Specifications

CD247 (CD3 zeta)
Murine
Flow Cytometry (Intracellular Staining)
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
5μL (0.03μg)/test
6B10.2
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer