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CD243 (ABCB1) Mouse anti-Human, FITC, Clone: UIC2, eBioscience™

Mouse Monoclonal Antibody

$157.08 - $368.28

Specifications

Antigen CD243 (ABCB1)
Clone UIC2
Host Species Murine
Gene Alias P-glycoprotein-1, MDR1
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122110 Life Technologies
LS11243941
25 Tests Each for $157.08
501122111 Life Technologies
LS11243942
100 Tests Each for $368.28
Specifications

Description

This monoclonal antibody reacts with human Multidrug Resistant (MDR)-1, which is also known as P-glycoprotein (Pgp) and CD243. A 170kDa transmembrane protein, MDR-1 is an ATP-dependent efflux pump for lipophilic compounds, including anti-cancer drugs. Expression of MDR-1 has been shown to correlate with multidrug resistance. In fact, tumor resistance to chemotherapy has been linked to MDR-1 expression in many cancers. MDR-1 is expressed in a variety of tissues, including the brain, kidney, liver, pancreas, and testes. Within the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes.

This antibody has been reported to inhibit MDR1-mediated efflux.
Description & Specifications

Specifications

CD243 (ABCB1)
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
UIC2
P-glycoprotein-1, MDR1
Flow Cytometry
FITC
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.5μg)/test