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CD24 Mouse anti-Human, PE, Clone: eBioSN3 (SN3 A5-2H10), eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  Life Technologies LS12024742

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Catalog No. 501129573



Description

Description

Description: The SN3 monoclonal antibody reacts with the human CD24 molecule, also known as Heat Stable Antigen (HSA). This 35-50 kDa molecule is anchored in the plasma membrane via phosphatidylinositol and is expressed by erythrocytes, thymocytes, peripheral lymphocytes and myeloid lineage. It has been reported that P-selectin (CD62P) binds to CD24. Applications Reported: The SN3 antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioSN3 (SN3 A5-2H10) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin′s lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.
Specifications

Specifications

CD24
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P25063
CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24A; FLJ22950; FLJ43543; MGC75043
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioSN3 (SN3 A5-2H10)
PE
CD24
Liquid
CD24
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
100133941
Documents

For Research Use Only.