missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD23 Mouse anti-Human, eFluor® 450, Clone: EBVCS2, eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  Life Technologies LS48023841

Catalog No. 501129318



Description

Description

Description: The EBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein. CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells and at low levels on T, NK, langerhans cells and platelet

CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Specifications

Specifications

CD23
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P06734
CD23, CD23A, CLEC4J, FCE2, IGEBF, BLAST-2, C-type lectin domain family 4, member J, CD23 antigen, fc-epsilon-RII, immunoglobulin E-binding factor, low affinity immunoglobulin epsilon Fc receptor, lymphocyte IgE receptor
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
EBVCS2
eFluor® 450
FCER2
Liquid
FCER2
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
2208
Documents

For Research Use Only.